Feasibility and Utility of Anatomical and Physiological Evaluation of Coronary Disease With Cardiac CT in Severe Aortic Stenosis (FUTURE-AS Registry): Rationale and Design.

ABSTRACT:

Background

Coronary artery disease (CAD) in patients with severe aortic stenosis (AS) is common and may be associated with worse outcomes. Computed tomography coronary angiography (CTCA) and fractional flow reserve derived from computed tomography (FFR_CT) are tools for comprehensive coronary assessment. The utility and safety of CTCA and FFR_CT in the work-up for transcatheter aortic valve replacement (TAVR) is not established, especially in an evolving landscape that involves younger TAVR patients. The FUTURE-AS Registry will assess the utility and safety of cardiac-optimized CTCA and FFR_CT to evaluate CAD and guide referral for downstream invasive coronary angiography (ICA) in patients with severe AS being considered for TAVR.

Methods

FUTURE

SUBMITTER: Khoo JK 

PROVIDER: S-EPMC11308847 | biostudies-literature | 2024 Mar

REPOSITORIES: biostudies-literature