Renal Impairment of Proximal Tubular Injury Caused by Red Yeast Rice Supplement: Report of 2 Cases.

ABSTRACT:

Introduction

Drug-induced tubulointerstitial injury is a common cause of renal impairment. Since the mechanisms of drug-induced tubular injury are diverse, various treatment approaches are needed according to the pathogenesis. Renal biopsy is indispensable to determine not only the pathological diagnosis, but also the underlying mechanism, and to guide appropriate treatment. Most recently, one of the red yeast supplements has been widely highlighted as a novel cause of tubular damage, mainly in Japan and Asia. However, neither detailed pathological findings nor the mechanism of renal impairment has been sufficiently reported.

Case presentation

Two cases of renal impairment after taking red yeast supplement internally are presented. Both cases showed renal dysfunction with lo

SUBMITTER: Takeuchi K 

PROVIDER: S-EPMC11309756 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature