Trends in uterine cancer incidence in the United States: The contribution of age, period and cohort effects.

ABSTRACT:

Objective

In the U.S., uterine cancer incidence is rising, with racial and ethnic minorities experiencing the largest increases. We performed age-period-cohort analyses using novel methods to examine the contribution of age at diagnosis (age), year of diagnosis (period), and birth cohort (cohort), to trends in uterine cancer incidence.

Methods

We used uterine cancer incidence data from the Surveillance, Epidemiology, and End Result (SEER) 12 database (1992-2019), and performed hysterectomy-correction. We generated hexamaps to visualize age, period, and cohort effects, and used mutual information to estimate the percent contribution of age, period, and cohort effects, individually and combined, on uterine cancer incidence, overall and by race and ethnicity and histology.

R

SUBMITTER: Ferris JS 

PROVIDER: S-EPMC11309905 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature