Amine-reactive crosslinking enhances type 0 collagen hydrogel properties for regenerative medicine.

ABSTRACT:

Introduction

Collagen is extensively utilised in regenerative medicine due to its highly desirable properties. However, collagen is typically derived from mammalian sources, which poses several limitations, including high cost, potential risk of immunogenicity and transmission of infectious diseases, and ethical and religious constraints. Jellyfish-sourced type 0 collagen represents a safer and more environmentally sustainable alternative collagen source.

Methods

Thus, we investigated the potential of jellyfish collagen-based hydrogels, obtained from Rhizostoma pulmo (R. pulmo) jellyfish, to be utilised in regenerative medicine. A variety of R. pulmo collagen hydrogels (RpCol hydrogels) were formed by adding a range of chemical crosslinking agents and their physicochemical a

SUBMITTER: Salthouse D 

PROVIDER: S-EPMC11310005 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature