Association between waist circumference and chronic pain: insights from observational study and two-sample Mendelian randomization.

ABSTRACT:

Background

Current research offers limited clarity on the correlation between waist circumference and chronic pain prevalence.

Objective

This investigation seeks to elucidate the potential relationship between waist circumference and chronic pain and their causal association.

Methods

An observational study was conducted, leveraging data from the National Health and Nutrition Examination Survey (NHANES) collected between 2001 and 2004. The multivariable logistic regression was used to assess the relationship between waist circumference and chronic pain. Furthermore, a meta-analysis of Mendelian Randomization (MR) was applied to explore a causal relationship between waist circumference and pain.

Results

The observational study, post multivariable adjustment, indi

SUBMITTER: Xu T 

PROVIDER: S-EPMC11310123 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature