An acute coronary syndrome in an unusual patient: analysing cisplatin toxicity-a case report and review of the literature.

ABSTRACT:

Background

Germ cell tumours (GCT) are the most common malignancy affecting young adult men. The introduction of cisplatin-based chemotherapy in recent decades has significantly changed the prognosis of these malignant tumours into highly curable cancer, even in the setting of advanced disease. However, in the last decade, the success of these chemotherapy regimens in curing GCTs has been slowed by a growing recognition of their important late toxicities, such as cardiovascular disease.

Case summary

We present the case of a 23-year-old male, recently diagnosed with a mixed non-seminomatous testicular germinal tumour, on stage IIIA (pT3 cN2 cM1a), with retroperitoneal adenopathies and pulmonary metastases. After performing a right inguinal orchiectomy, he started chemotherapy

SUBMITTER: Erquicia Peralt J 

PROVIDER: S-EPMC11310699 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature