Understanding the Solid-State Structure of Riboflavin through a Multitechnique Approach.

ABSTRACT: Crystalline riboflavin (vitamin B₂) performs an important biological role as an optically functional material in the tapetum lucidum of certain animals, notably lemurs and cats. The tapetum lucidum is a reflecting layer behind the retina, which serves to enhance photon capture and vision in low-light settings. Motivated by the aim of rationalizing its biological role, and given that the structure of biogenic solid-state riboflavin remains unknown, we have used a range of experimental and computational techniques to determine the solid-state structure of synthetic riboflavin. Our multitechnique approach included microcrystal XRD, powder XRD, three-dimensional electron diffraction (3D-ED), high-resolution solid-state ¹³C NMR spectroscopy, and dispersion-au

SUBMITTER: Smalley CJH 

PROVIDER: S-EPMC11311124 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature