Evaluating enrollment and representation in COVID-19 and HIV vaccine clinical trials.

ABSTRACT:

Background

Vaccine clinical trials should strive to recruit a racially, socioeconomically, and ethnically diverse range of participants to ensure appropriate representation that matches population characteristics. Yet, full inclusion in research is often limited.

Methods

A single-center retrospective study was conducted of adults enrolled at Brigham and Women's Hospital (Boston, MA) between July 2020 and December 2021. Demographic characteristics, including age, race, ethnicity, ZIP code, and sex assigned at birth, were analyzed from both HIV and COVID-19 vaccine trials during the study period, acknowledging the limitations to representation under these parameters. We compared the educational attainment of vaccine trial participants to residents of the Massachusetts metropol

SUBMITTER: Lezo Ramirez D 

PROVIDER: S-EPMC11311253 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature