Audiovestibular Dysfunction in Systemic Lupus Erythematosus Patients: A Systematic Review.

ABSTRACT: Audiovestibular dysfunction in patients with systemic lupus erythematosus has been underestimated for decades. Systemic lupus erythematosus can affect both the auditory and vestibular systems simultaneously. Several potential pathophysiological mechanisms behind systemic lupus erythematosus-related audiovestibular dysfunction have been proposed, including antibody-mediated immune responses, cell-mediated cytotoxicity, immune complex deposition in microvessels, central involvement in the audiovestibular pathway, and ototoxicity from medications used in systemic lupus erythematosus treatment. Currently available tests to evaluate audiovestibular function in systemic lupus erythematosus patients are neither specific nor sensitive. Nevertheless, there is no consensus regarding the efficacy of

SUBMITTER: Chen JJ 

PROVIDER: S-EPMC11311441 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature