A Preliminary Study on Factors That Drive Patient Variability in Human Subcutaneous Adipose Tissues.

ABSTRACT: Adipose tissue is a dynamic regulatory organ that has profound effects on the overall health of patients. Unfortunately, inconsistencies in human adipose tissues are extensive and multifactorial, including large variability in cellular sizes, lipid content, inflammation, extracellular matrix components, mechanics, and cytokines secreted. Given the high human variability, and since much of what is known about adipose tissue is from animal models, we sought to establish correlations and patterns between biological, mechanical, and epidemiological properties of human adipose tissues. To do this, twenty-six independent variables were cataloged for twenty patients, which included patient demographics and factors that drive health, obesity, and fibrosis. A factorial analysis for mixed data (FAMD

SUBMITTER: DeBari MK 

PROVIDER: S-EPMC11311805 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature