Study of microRNAs in Gingival Crevicular Fluid as Periodontal Diseases Biomarkers: Systematic Review.

ABSTRACT:

Aim

The aim of this review was to identify the microRNAs (miRNAs) present in gingival crevicular fluid (GCF) that can be used as biomarkers for the diagnosis of periodontal diseases, and to determine which of them has a higher diagnostic yield for periodontitis.

Methods

The review was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines (reference number CRD42024544648). The Pubmed, Scopus, Cochrane Library, Embase, Web of Science, and Google Scholar databases were searched for clinical studies conducted in humans investigating periodontal diseases and miRNAs in GCF. The methodological quality of the articles was measured with the Newcastle-Ottawa Scale.

Results

A total of 3222 references were identified in the initial

SUBMITTER: Cosin-Villanueva M 

PROVIDER: S-EPMC11311819 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature