Determinants of Guideline-Directed Medical Therapy Implementation During Heart Failure Hospitalization.

ABSTRACT:

Background

Despite evidence that guideline-directed medical therapies (GDMTs) improve outcomes in patients with heart failure (HF) with reduced ejection fraction (HFrEF), implementation remains suboptimal.

Objectives

The purpose of this study was to measure GDMT implementation during acute HFrEF hospitalization, evaluate the association between socioeconomic factors and GDMT implementation, and assess the association of GDMT utilization with subsequent clinical events.

Methods

Retrospective determination of GDMT utilization using a modified optimal medical therapy (mOMT) score (which accounts for specific contraindications to drugs) during unplanned HF hospitalization of consecutive adult patients with new-onset or previously diagnosed HFrEF from 2017 to 2018. Outcome

SUBMITTER: Margolin E 

PROVIDER: S-EPMC11312039 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature