Performance of [¹⁸F]FDG PET/CT in Diagnosing Cyst Infections in Patients with Autosomal Dominant Polycystic Kidney Disease: A Systematic Review and a Bivariate Meta-Analysis.

ABSTRACT:

Background

Fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) has been suggested as a useful imaging method for diagnosing cyst infections in patients with autosomal dominant polycystic kidney disease (ADPKD). The aim of this article is to provide evidence-based data in this setting.

Methods

A systematic literature review (exploring several bibliographic databases) and a bivariate meta-analysis were carried out to calculate the pooled diagnostic performance of [¹⁸F]FDG PET/CT in diagnosing probable cyst infection in ADPKD.

Results

Ten studies (282 PET/CT scans and 249 patients) were included in the analysis. The pooled sensitivity and specificity of [¹⁸F]FDG PET/CT in this setting were 84.

SUBMITTER: Treglia G 

PROVIDER: S-EPMC11312050 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature