Diagnostic efficacy of [^99mTc]Tc-PSMA SPECT/CT for prostate cancer: a meta-analysis.

ABSTRACT:

Background

Prompt and accurate diagnosis of prostate cancer (PCa) is of paramount importance for effective treatment planning. While Gallium-68 labeled prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) has proven efficacy in detecting PCa, limited availability poses challenges. As a potential alternative, [^99mTc]Tc-PSMA single photon emission computed tomography (SPECT)/computed tomography (CT) holds promise. This systematic review and meta-analysis aimed to evaluate the diagnostic value of [^99mTc]Tc-PSMA SPECT/CT for prostate cancer.

Methods

A comprehensive search of PubMed, Cochrane, EMBASE, Scopus, Ovid, and Web of Science databases was conducted until July 2024. Sensitivity and specificity data wer

SUBMITTER: Wang Q 

PROVIDER: S-EPMC11312272 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature