Central Venous Pressure and Impaired Renal Function in Children and Young Adults With Cardiovascular Disease.

ABSTRACT:

Background

Traditionally, low cardiac output has been considered the primary hemodynamic driver of renal function and injury. Adult data suggest that central venous pressure (CVP) is a more important factor.

Objectives

The authors hypothesized that in children with cardiovascular disease, higher CVP predicts lower estimated glomerular filtration rate (eGFR) and worsening renal function (WRF).

Methods

We performed a single-center cohort study of patients aged 3 months to 21 years with biventricular circulation undergoing cardiac catheterization. Pearson's correlation and linear and Cox regression analyses were performed to determine associations with eGFR at the time of catheterization and WFR within 180 days after catheterization.

Results

312 patients had media

SUBMITTER: Olsen J 

PROVIDER: S-EPMC11312305 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature