Reemergence of Oropouche virus between 2023 and 2024 in Brazil.

ABSTRACT:

Background

Oropouche virus (OROV; species Orthobunyavirus oropoucheense) is an arthropod-borne virus that has caused outbreaks of Oropouche fever in Central and South America since the 1950s. This study investigates virological factors contributing to the reemergence of Oropouche fever in Brazil between 2023 and 2024.

Methods

In this study, we combined OROV genomic, molecular, and serological data from Brazil from 1 January 2015 to 29 June 2024, along with in vitro and in vivo characterization. Molecular screening data included 93 patients with febrile illness between January 2023 and February 2024 from the Amazonas State. Genomic data comprised two genomic OROV sequences from patients. Serological data were obtained from neutralizing antibody tests comp

SUBMITTER: Scachetti GC 

PROVIDER: S-EPMC11312653 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature