High cardiovascular mortality risk among older merkel cell carcinoma patients.

ABSTRACT:

Objective

Previous research has primarily focused on the incidence and mortality rates of Merkel cell carcinoma (MCC), neglecting the examination of cardiovascular mortality (CVM) risk among survivors, particularly older patients. This study aims to assess the risk of CVM in older individuals diagnosed with MCC.

Methods

Data pertaining to older MCC patients were obtained from the Surveillance, Epidemiology, and End Results database (SEER). CVM risk was measured using standardized mortality ratio (SMR) and cumulative mortality. Multivariate Fine-Gray's competing risk model was utilized to evaluate the risk factors contributing to CVM.

Results

Among the study population of 2,899 MCC patients, 465 (16.0%) experienced CVM during the follow-up period. With the prolongation

SUBMITTER: Huang JN 

PROVIDER: S-EPMC11312700 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature