Sex Differences in the Association Between Vascular Risk Factors and Cognitive Decline: A UK Biobank Study.

ABSTRACT:

Background

Age-related cognitive decline is accelerated by vascular risk factors for cerebral small vessel disease. However, the association of vascular risk factors with cerebral small vessel disease contributing to the sex differences in cognitive decline remains unclear.

Objectives

The purpose of this study was to evaluate sex differences in cognitive decline and the association between vascular risk factors and cognitive decline by sex.

Methods

We used data from the UK Biobank (>55 years of age; n = 19,067) to assess cognitive tests (executive function, processing speed, and memory) while adjusting for baseline measurements to examine how vascular risk factors affect cognition. A univariate regression analysis was used to assess sex differences at the first time p

SUBMITTER: Kaur A 

PROVIDER: S-EPMC11312777 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature