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Impact of Sex on Severity Assessment and Cardiac Remodeling in Primary Mitral Regurgitation.


ABSTRACT:

Background

Women with severe primary mitral regurgitation (MR) have lower surgery rates than men and could suffer from delayed referral for mitral valve (MV) intervention, exposing them to an increased risk of postoperative adverse outcomes.

Objectives

The purpose of this study was to assess the sex-based differences in patients with primary MR.

Methods

The study sample consisted of 420 patients (median age: 62 years, 26% women) with primary MR due to valve prolapse referred for preoperative assessment who underwent transthoracic echocardiography (TTE) and cardiac magnetic resonance (CMR) imaging. Multiple endpoints (abnormally increased left ventricular size, NYHA functional class III/IV, severe left atrial [LA] dilatation, pulmonary hypertension) were studied using

SUBMITTER: Altes A 

PROVIDER: S-EPMC11312794 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature