Influencing factors for surgical treatment in neonatal necrotizing enterocolitis: a systematic review and meta-analysis.

ABSTRACT:

Background

Necrotizing enterocolitis (NEC) is a complex disease characterized by gastrointestinal inflammation and is one of the most common gastrointestinal emergencies in neonates. Mild to moderate cases of NEC require medical treatment, whereas severe cases necessitate surgical intervention. However, evidence for surgical indications is limited and largely dependent on the surgeon's experience, leading to variability in outcomes. The primary aim of this study is to identify the risk factors for surgical intervention in neonatal NEC, which will aid in predicting the optimal timing for surgical intervention.

Methods

A literature search was conducted in PubMed, Embase, and Web of Science databases for case-control studies exploring risk factors for NEC requiring surgical int

SUBMITTER: Wang D 

PROVIDER: S-EPMC11312808 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature