The Ongoing Relationship Between Offspring Congenital Heart Disease and Preeclampsia Across Pregnancies.

ABSTRACT:

Background

Prior literature has described an association between preeclampsia and offspring congenital heart disease (CHD), while suggesting there may be a stronger relationship in individuals with early preeclampsia.

Objectives

The authors sought to explore the relationship between offspring CHD and preeclampsia among pregnancies in a population-based study.

Methods

Retrospective cohort study all singleton pregnancies delivered in the state of California 2000 to 2012. We included singleton births with gestational ages of 23 to 42 weeks and excluded pregnancies complicated by pre-existing diabetes or identified fetal chromosomal anomalies. We used multivariable logistic regression to estimate ORs for associations between offspring CHD and preeclampsia. Further subanal

SUBMITTER: Katlaps I 

PROVIDER: S-EPMC11313037 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature