Transoral Robotic Surgery and Human Papillomavirus Infection: Impact on Oropharyngeal Cancer Prognosis.

ABSTRACT: Background/Objective: The incidence of oropharyngeal cancer (OPC) remains significant, with a rising prevalence of HPV-positive (HPV⁺) cases, underscoring the growing importance of appropriate treatment approaches for this condition. While HPV⁺ OPC typically exhibits a more favorable prognosis than HPV-negative (HPV^-) OPC, certain HPV⁺ OPC patients still face adverse outcomes. This study aimed to assess the effectiveness of TORS versus traditional surgery in treating OPC patients and investigate the prognostic implications of specific variants in the HPV genome. Methods: The clinical information, including pathological features, treatments, and outcomes (death), of 135 OPC patients treated with traditional surgery from 2008 to 2018

SUBMITTER: Chen J 

PROVIDER: S-EPMC11313069 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature