Self-Assembly of Hydrophobic Hyperbranched PLMA Homopolymer with -COOH End Groups as Effective Nanocarriers for Bioimaging Applications.

ABSTRACT: Nanomedicine is a discipline of medicine that applies all aspects of nanotechnology strategies and concepts for treatment and screening possibilities. Synthetic polymer nanostructures are among the many nanomedicine formulations frequently studied for their potential as vectors. Bioimaging is a valuable diagnostic tool, thus, there is always a demand for new excipients/nanocarriers. In this study, hydrophobic hyperbranched poly(lauryl methacrylate) (PLMA) homopolymers comprised of highly hydrophobic LMA moieties with -COOH polar end groups were synthesized by employing reversible addition-fragmentation chain transfer (RAFT) polymerization. Ethylene glycol dimethacrylate (EGDMA) was utilized as the branching agent. End groups are incorporated through the RAFT agent utilized. The resulting a

SUBMITTER: Gerardos AM 

PROVIDER: S-EPMC11314538 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature