Cosmetic Preservative Potential and Chemical Composition of Lafoensia replicata Pohl. Leaves.

ABSTRACT: The study evaluated the preservative potential of Lafoensia replicata Pohl. leaf extracts in cosmetics, highlighting their antioxidant, antimicrobial, and in vitro cytotoxic activities for ethanolic extract prepared by the maceration and tincture method. Total phenol content showed a higher phenol concentration in ethanolic extract and tinctures, and by LC-MS/MS-ESI-QTOF analysis, flavonoids, hydrolyzed tannins, and phenolic acids were identified. The ethanolic extract and tincture showed high antimicrobial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Candida albicans (MIC < 50 µg mL^-1), high antioxidant activity (EC₅₀ < 50 µg mL^-1 in the DPPH method, and results > 450 µmol trolox equivalent in the ABTS and

SUBMITTER: Lima DM 

PROVIDER: S-EPMC11314560 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature