Clinical characteristics of enteric fever and performance of TUBEX TF IgM test in Indonesian hospitals.

ABSTRACT:

Background

Accurate diagnosis of enteric fever is challenging, particularly in low- and middle-income countries, due to the overlap of clinical and laboratory features with other pathogens. To better understand the difficulties in enteric fever diagnosis, we evaluated the characteristics of patients clinically diagnosed with enteric fever and the real-world performance of TUBEX TF, one of the most used tests in Indonesia.

Methodology/principal findings

Patients were recruited through the AFIRE (Etiology of Acute Febrile Illness Requiring Hospitalization) study at eight Indonesian hospitals. Blood culture was performed for all patients, and TUBEX TF was performed for suspected enteric cases. Salmonella PCR and ELISA tests were performed at a reference lab. Sensitivity and spe

SUBMITTER: Nurmawati S 

PROVIDER: S-EPMC11315288 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature