The role of circular RNAs (circRNAs) as a prognostic factor in lung cancer: a meta-analysis.

ABSTRACT:

Background

Lung cancer is a leading cause of cancer-related death worldwide. Among various histological types of lung cancer, majority are non-small cell lung cancer (NSCLC) which account for > 80%. Circular RNAs (circRNAs) are widely expressed in various cancers including lung cancer and implicated in tumourigenesis and cancer progression. This study aimed to systematically evaluate the prognostic values of circRNAs in lung cancer.

Methods

A systematic literature search was done in PubMed, Embase, and MEDLINE databases to select the eligible studies which reported the association between the expression of circRNAs and overall survival (OS) or disease-free survival (DFS) in histopathologically diagnosed lung cancer patients. The pooled hazard ratio (HR) and 95% confidence in

SUBMITTER: Ahsan S 

PROVIDER: S-EPMC11316314 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature