Immune and inflammation features of severe and critical Omicron infected patients during Omicron wave in China.

ABSTRACT:

Objective

The current study aimed to investigate the baseline immune and inflammatory features and in-hospital outcomes of patients infected with the Omicron variant (PIWO) who presented with different disease severities during the first wave of mass Omicron infections in the Chinese population has occurred.

Method

A cross-sectional study was conducted on 140 hospitalized PIWO between December 11, 2022, and February 16, 2023. The clinical features, antibodies against SARS-CoV-2, immune cells, and inflammatory cytokines among mildly, severely, and critically ill PIWO at baseline and during follow-up period were compared.

Result

Patients with severe (n = 49) and critical (n = 35) disease were primarily male, needed invasive mechanical ventilation treatment, and exhibite

SUBMITTER: Liu Y 

PROVIDER: S-EPMC11316362 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature