Comparative transcriptomics reveals a highly polymorphic Xanthomonas HrpG virulence regulon.

ABSTRACT:

Background

Bacteria of the genus Xanthomonas cause economically significant diseases in various crops. Their virulence is dependent on the translocation of type III effectors (T3Es) into plant cells by the type III secretion system (T3SS), a process regulated by the master response regulator HrpG. Although HrpG has been studied for over two decades, its regulon across diverse Xanthomonas species, particularly beyond type III secretion, remains understudied.

Results

In this study, we conducted transcriptome sequencing to explore the HrpG regulons of 17 Xanthomonas strains, encompassing six species and nine pathovars, each exhibiting distinct host and tissue specificities. We employed constitutive expression of plasmid-borne hrpG*, which encodes a constitutively active form of

SUBMITTER: Monnens TQ 

PROVIDER: S-EPMC11316434 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature