Effects of Psychedelics in Older Adults: A Prospective Cohort Study.

ABSTRACT:

Objective

Affective symptoms such as anxiety, low mood, and loneliness are prevalent and highly debilitating symptoms among older adults (OA). Serotonergic psychedelics are currently investigated as novel interventions for affective disorders, yet little is known regarding their effects in OA. We investigated the mental health effects and psychological mechanisms of guided psychedelic group experiences in OA and a matched sample of younger adults (YA).

Methods

Using a prospective observational cohort design, we identified 62 OA (age ≥60 years) and 62 matched YA who completed surveys two weeks before, a day, two weeks, four weeks, and six months after a psychedelic group session. Mixed linear regression analyses were used to investigate longitudinal well-being changes, as wel

SUBMITTER: Kettner H 

PROVIDER: S-EPMC11316630 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature