Exploring the role of blood pressure in the black-white disparity in cardiovascular disease mortality: a causal mediation analysis.

ABSTRACT:

Background

Cardiovascular diseases (CVDs) are the leading cause of death in the USA, and high blood pressure is a major risk factor for CVD. Despite the overall declining rates of CVD mortality in the USA in recent years, marked disparities between racial and ethnic groups persist, with black adults having a higher mortality rate than white adults. We investigated the extent to which blood pressure mediated the black-white disparity in CVD mortality.

Methods

Data came from the Multi-Ethnic Study of Atherosclerosis, a diverse longitudinal cohort. We included 1325 black and 2256 white community-based adults aged 45-80 years free of clinical CVD at baseline and followed for 14 years. We used causal mediation analysis to estimate the effect of race on CVD mortality that was medi

SUBMITTER: Zhao F 

PROVIDER: S-EPMC11316631 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature