Chronic automated red cell exchange therapy for sickle cell disease.

ABSTRACT:

Background

The data to support chronic automated red cell exchange (RCE) in sickle cell disease (SCD) outside of stroke prevention, is limited, especially in adults.

Study design and methods

A retrospective analysis was conducted of patients with SCD who were referred for chronic RCE at our institution over a 10-year period. Data that were evaluated included patient demographics, referral indications, and procedural details (e.g., vascular access, adverse events, etc.). In a subanalysis, the number of annual acute care encounters during 3 years of chronic RCE was compared with that in the year preceding the first RCE.

Results

A total of 164 patients were referred for chronic RCE: median age was 28 years (interquartile range [IQR] = 22-36) at referral and 60% were fema

SUBMITTER: Zakieh A 

PROVIDER: S-EPMC11316647 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature