Personalized Versus Precision Nanomedicine for Treatment of Ovarian Cancer.

ABSTRACT: The response to treatment is substantially varied between individual patients with ovarian cancer. However, chemotherapy treatment plans rarely pay sufficient attention to the mentioned factors. Instead, standardized treatment protocols are usually employed for most ovarian cancer patients. Variations in an individual's sensitivity to drugs significantly limit the effectiveness of treatment in some patients and lead to severe toxicities in others. In the present investigation, a nanotechnology-based approach for personalized treatment of ovarian carcinoma (the most lethal type of gynecological cancer) constructed on the individual genetic profile of the patient's tumor is developed and validated. The expression of predefined genes and proteins is analyzed for each patient sample. Finally,

SUBMITTER: Garbuzenko OB 

PROVIDER: S-EPMC11316847 | biostudies-literature | 2024 Oct

REPOSITORIES: biostudies-literature