Regulatory T cells and immune escape in HCC: understanding the tumor microenvironment and advancing CAR-T cell therapy.
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ABSTRACT:
SUBMITTER: Du G
PROVIDER: S-EPMC11317284 | biostudies-literature | 2024
REPOSITORIES: biostudies-literature
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Regulatory T cells and immune escape in HCC: understanding the tumor microenvironment and advancing CAR-T cell therapy.
Du Guangtan G Dou Cunmiao C Sun Peng P Wang Shasha S Liu Jia J Ma Leina L
Frontiers in immunology 20240729
Liver cancer, which most commonly manifests as hepatocellular carcinoma (HCC), is the sixth most common cancer in the world. In HCC, the immune system plays a crucial role in the growth and proliferation of tumor cells. HCC achieve immune escape through the tumor microenvironment, which significantly promotes the development of this cancer. Here, this article introduces and summarizes the functions and effects of regulatory T cells (Tregs) in the tumor microenvironment, highlighting how Tregs in ...[more]
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