Restriction of growth and biofilm formation of ESKAPE pathogens by caprine gut-derived probiotic bacteria.

ABSTRACT: The accelerated rise in antimicrobial resistance (AMR) poses a significant global health risk, necessitating the exploration of alternative strategies to combat pathogenic infections. Biofilm-related infections that are unresponsive to standard antibiotics often require the use of higher-order antimicrobials with toxic side effects and the potential to disrupt the microbiome. Probiotic therapy, with its diverse benefits and inherent safety, is emerging as a promising approach to prevent and treat various infections, and as an alternative to antibiotic therapy. In this study, we isolated novel probiotic bacteria from the gut of domestic goats (Capra hircus) and evaluated their antimicrobial and anti-biofilm activities against the 'ESKAPE' group of pathogens. We performed compr

SUBMITTER: Saini P 

PROVIDER: S-EPMC11317286 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature