Integrated metabolome and transcriptome analysis provide insight into the biosynthesis of flavonoids in Panax japonicus.

ABSTRACT: Panax japonicus is an important medicinal plant, and flavonoids are one of its main secondary metabolites. In this study, the main roots, fibrous roots, stems, leaves and flowers of P. japonicus were analyzed using transcriptomics and widely targeted metabolomics. Through correlation analysis of transcription and metabolism, the flavonoid biosynthesis pathway in P. japonicus was analyzed, and the accumulation of flavonoid metabolites and the expression of related genes were investigated. Metabolomics revealed a total of 209 flavonoid metabolites in P. japonicus, among which flavonoids, flavonols, flavanones and flavanonols significantly accumulated in the flowers and leaves. Transcriptome sequencing revealed that key genes in the flavonoid pathway exhibited incr

SUBMITTER: Chen C 

PROVIDER: S-EPMC11317393 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature