Treatment of spinal cord injury with biomaterials and stem cell therapy in non-human primates and humans.

ABSTRACT: Spinal cord injury results in the loss of sensory, motor, and autonomic functions, which almost always produces permanent physical disability. Thus, in the search for more effective treatments than those already applied for years, which are not entirely efficient, researches have been able to demonstrate the potential of biological strategies using biomaterials to tissue manufacturing through bioengineering and stem cell therapy as a neuroregenerative approach, seeking to promote neuronal recovery after spinal cord injury. Each of these strategies has been developed and meticulously evaluated in several animal models with the aim of analyzing the potential of interventions for neuronal repair and, consequently, boosting functional recovery. Although the majority of experimental research ha

SUBMITTER: Olaya AMS 

PROVIDER: S-EPMC11317961 | biostudies-literature | 2025 Feb

REPOSITORIES: biostudies-literature