Peri-hematomal edema shape features related to 3-month outcome in acute supratentorial intracerebral hemorrhage.

ABSTRACT:

Introduction

Perihematomal edema (PHE) represents secondary brain injury and a potential treatment target in intracerebral hemorrhage (ICH). However, studies differ on optimal PHE volume metrics as prognostic factor(s) after spontaneous, non-traumatic ICH. This study examines associations of baseline and 24-h PHE shape features with 3-month outcomes.

Patients and methods

We included 796 patients from a multicentric trial dataset and manually segmented ICH and PHE on baseline and follow-up CTs, extracting 14 shape features. We explored the association of baseline, follow-up, difference (baseline/follow-up) and temporal rate (difference/time gap) of PHE shape changes with 3-month modified Rankin Score (mRS) - using Spearman correlation. Then, using multivariable analysis, we d

SUBMITTER: Dierksen F 

PROVIDER: S-EPMC11318427 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature