The observational EURACAN prospective clinical registry dedicated to epithelioid hemangioendothelioma: The protocol of an international and collaborative effort on an ultra-rare entity.

ABSTRACT:

Introduction

Epithelioid hemangioendothelioma (EHE) is an ultra-rare sarcoma, marked by distinctive molecular and pathological features and with a variable clinical behavior. Its natural history is still partially understood, reliable prognostic and predictive factors are lacking and many questions are still open on the optimal management. In the context of EURACAN, a prospective registry specifically dedicated to EHE was developed and launched with the aim of providing, through high-quality prospective data collection, a better understanding of this disease.

Study design

Registry-based cohort study including only new cases of patients with a pathological and molecularly confirmed diagnosis of EHE.

Objectives

To improve the understanding of EHE natural history, valida

SUBMITTER: Frezza AM 

PROVIDER: S-EPMC11318912 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature