Genetic risk factors for COVID-19 and influenza are largely distinct.

ABSTRACT: Coronavirus disease 2019 (COVID-19) and influenza are respiratory illnesses caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza viruses, respectively. Both diseases share symptoms and clinical risk factors¹, but the extent to which these conditions have a common genetic etiology is unknown. This is partly because host genetic risk factors are well characterized for COVID-19 but not for influenza, with the largest published genome-wide association studies for these conditions including >2 million individuals² and about 1,000 individuals^3-6, respectively. Shared genetic risk factors could point to targets to prevent or treat both infections. Through a genetic study of 18,334 cases with a positive test for influenza and 276

SUBMITTER: Kosmicki JA 

PROVIDER: S-EPMC11319199 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature