Memory function in autoimmune encephalitis: a cross-sectional prospective study utilising multiple memory paradigms.

ABSTRACT:

Background and objective

Autoimmune encephalitis (AE) is often associated with clinically significant memory impairment. This study aimed to evaluate memory in a cross-sectional prospective AE cohort using multiple memory paradigms.

Methods

52 patients (50% seropositive) meeting Graus criteria for possible AE were prospectively recruited between October 2019 and August 202. A comprehensive examination of memory was performed, including tests of supraspan verbal memory (list learning), logicosemantic memory (story learning), figural memory (learning of geometric designs), and verbal associative learning (verbal paired associates). Memory scores were compared to demographically adjusted normative data. Pattern analysis was conducted to assist in the identification of patterns

SUBMITTER: Griffith SP 

PROVIDER: S-EPMC11319369 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature