Plant viruses exploit insect salivary GAPDH to modulate plant defenses.

ABSTRACT: Salivary proteins of insect herbivores can suppress plant defenses, but the roles of many remain elusive. One such protein is glyceraldehyde-3-phosphate dehydrogenase (GAPDH) from the saliva of the Recilia dorsalis (RdGAPDH) leafhopper, which is known to transmit rice gall dwarf virus (RGDV). Here we show that RdGAPDH was loaded into exosomes and released from salivary glands into the rice phloem through an exosomal pathway as R. dorsalis fed. In infected salivary glands of R. dorsalis, the virus upregulated the accumulation and subsequent release of exosomal RdGAPDH into the phloem. Once released, RdGAPDH consumed H₂O₂ in rice plants owing to its -SH groups reacting with H₂O₂. This reduction in H₂O₂ of rice plant facilitate

SUBMITTER: Wang X 

PROVIDER: S-EPMC11319438 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature