Decision theoretical foundations of clinical practice guidelines: an extension of the ASH thrombophilia guidelines.

ABSTRACT:

Abstract

Decision analysis can play an essential role in informing practice guidelines. The American Society of Hematology (ASH) thrombophilia guidelines have made a significant step forward in demonstrating how decision modeling integrated within Grading of Recommendations Assessment, Developing, and Evaluation (GRADE) methodology can advance the field of guideline development. Although the ASH model was transparent and understandable, it does, however, suffer from certain limitations that may have generated potentially wrong recommendations. That is, the panel considered 2 models separately: after 3 to 6 months of index venous thromboembolism (VTE), the panel compared thrombophilia testing (A) vs discontinuing anticoagulants (B) and testing (A) vs recommending indefinite anticoag

SUBMITTER: Djulbegovic B 

PROVIDER: S-EPMC11319831 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature