Rheumatic and Musculoskeletal Diseases and Risk of Dementia: A Nested Case-Control Study.

ABSTRACT:

Objective

To investigate the associations between rheumatic and musculoskeletal diseases (RMDs) and incident dementia using population register-based data.

Methods

This nested case-control study was conducted based on a cohort of residents in the Skåne region, Sweden, aged 50 years and older in 2009 without doctor-diagnosed dementia during 1998 to 2009 (n = 402,825). Individuals with a new main diagnosis of dementia during 2010 to 2019 were identified as incident patients with dementia (n = 22,131). Controls without diagnosed dementia were randomly matched 1:1 by sex, age, and Elixhauser comorbidity index using incidence density sampling. Separate conditional logistic regression analyses adjusted for confounders were fitted for the following RMDs, diagnosed at least 2 years

SUBMITTER: Kiadaliri A 

PROVIDER: S-EPMC11319920 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature