Correlation between initial alkaline phosphatase levels and overall survival in newly diagnosed multiple myeloma patients.

ABSTRACT:

Background

Alkaline phosphatase (ALP) reflects changes in the condition of multiple myeloma (MM) patients to some extent. However, the relationship of ALP in MM remains uncertain. Our study aimed to determine the association between initial ALP levels and overall survival in newly diagnosed MM patients.

Methods

Clinical data from 202 newly diagnosed MM patients at Beijing Chaoyang Hospital between 2012 and 2016 were collected. Baseline characteristics, disease progression staging, serum markers, and patient survival data were recorded. The cut-off value for ALP was calculated based on patient survival data, and patients were divided into groups. Differences in patients' 3- and 5-year survival rates, liver function, bone disease and other indicators among different groups wer

SUBMITTER: Tan J 

PROVIDER: S-EPMC11319959 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature