Crystallization of smooth amorphous calcium phosphate microspheres to core-shell hydroxyapatite microspheres.

ABSTRACT: Calcium phosphates (Ca-P) represent a significant class of biological minerals found in natural hard tissues. Crystallization through phase transformation of a metastable precursor is an effective strategy to guide the growth of crystalline Ca-P with exceptional functionality. Despite extensive research on Ca-P, the exact process during the crystallization of amorphous particles to hydroxyapatite (HA) remains elusive. Herein, pure HA microspheres with a core-shell structure are crystallized via dissolution and re-crystallization of smooth amorphous calcium phosphate (ACP) microspheres. The transformation is initiated with the increase of the hydrothermal treatment time in the presence of sodium trimetaphosphate and l-glutamic. The underlying mechanisms along with the kinetics of suc

SUBMITTER: Qi ML 

PROVIDER: S-EPMC11320051 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature