COVID-19 seropositive donors yield comparable post-lung transplant outcomes.

ABSTRACT:

Background

Recent reports have suggested that coronavirus disease 2019 (COVID-19) infection can cause pneumonitis even in the absence of clinical symptoms and COVID-19 associated pulmonary inflammation can persist resulting in long-term fibrosis. This single-center study utilized standardized immunological testing to determine whether lungs from COVID-19 seropositive donors, indicative of past COVID-19 infection, can be safely used for clinical transplantation.

Methods

The study included 90 consecutive lung transplant procedures incorporating donor serological testing for past COVID-19 infection. Donors were negative for active COVID-19 infection and met institutional criteria to be used for lung transplantation. The outcomes of lung transplant recipients were compared betwe

SUBMITTER: Kurihara C 

PROVIDER: S-EPMC11320287 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature