Applying mixed-integer linear programming to the non-coplanar beam angle optimization of intensity-modulated radiotherapy for liver cancer.

ABSTRACT:

Background

Currently, intensity-modulated radiation therapy (IMRT) is commonly used in radiotherapy clinics. However, designing a treatment plan with multiple beam angles depends on the experience of human planners, and is mostly achieved using a trial-and-error approach. It is preferrable but challenging to solve this issue automatically and mathematically using an optimization approach. The goal of this study is to develop a mixed-integer linear programming (MILP) approach for the beam angle optimization (BAO) of non-coplanar IMRT for liver cancer.

Methods

MILP models for the BAO of both coplanar and non-coplanar IMRT treatment plans were developed. The beam angles of the IMRT plans were first selected by the MILP model built using mathematical optimization software. Next,

SUBMITTER: Huang P 

PROVIDER: S-EPMC11320540 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature