Intervention portfolios analysis of Plasmodium vivax control in central China.

ABSTRACT:

Background

The effects of a diverse spectrum of malaria interventions were evaluated through a deterministic Plasmodium vivax transmission model. This approach aimed to provide theoretical evidence of the performance of these interventions once implemented for achieving malaria elimination.

Methods

An integrated intervention portfolio, including mass drug administration, insecticide treatment, and untreated bed nets, was analyzed through modeling. Additionally, data-driven calibration was implemented to infer coverages that effectively reproduced historical malaria patterns in China from 1971 to 1983.

Results

MDA utilizing primaquine emerged as the most effective single intervention, achieving a 70% reduction in malaria incidence when implemented at full coverage. Fur

SUBMITTER: Bi B 

PROVIDER: S-EPMC11321059 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature