The Association Between Prolactin Levels and Cognitive Function in Female Patients With Severe Mental Disorders.

ABSTRACT:

Objective

Cognition impairments are considered as a fundamental characteristic of severe mental disorders (SMD). Recent studies suggest that hyperprolactinemia may exert a detrimental influence on cognitive performance in patients with SMD. The objective of this study was to investigate the correlation between serum prolactin levels and cognitive function in female individuals diagnosed with SMD.

Methods

We conducted a study on 294 patients with SMD and 195 healthy controls, aged between 14 to 55 years old. Cognitive function was assessed using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS), while prolactin levels were measured in serum. Descriptive analysis and comparative analysis were performed to compare cognitive function and prolactin le

SUBMITTER: Xu Y 

PROVIDER: S-EPMC11321871 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature