Validation of a semi-quantitative scoring system and workflow for analysis of fluorescence quantification in companion animals.

ABSTRACT:

Significance

Many commercially available near-infrared (NIR) fluorescence imaging systems lack algorithms for real-time quantifiable fluorescence data. Creation of a workflow for clinical assessment and post hoc analysis may provide clinical researchers with a method for intraoperative fluorescence quantification to improve objective outcome measures.

Aim

Scoring systems and verified image analysis are employed to determine the amount and intensity of fluorescence within surgical specimens both intra and postoperatively.

Approach

Lymph nodes from canine cancer patients were obtained during lymph node extirpation following peritumoral injection of indocyanine green (ICG). First, a semi-quantitative assessment of surface fluorescence was evaluated. Images obtaine

SUBMITTER: Ram AS 

PROVIDER: S-EPMC11322124 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature